| Sep 06, 2010 | Houston Dynamo | | 1-2 | | San Jose Earthquakes | |
| | Sep 05, 2010 | Colorado Rapids | | 3-0 | | Chivas USA | |
| Sep 05, 2010 | DC United | | 0-1 | | Columbus Crew | |
| Sep 05, 2010 | FC Dallas | | 1-0 | | Toronto FC | |
| Sep 05, 2010 | New England Revolution | | 3-1 | | Seattle Sounders | |
| Sep 05, 2010 | Real Salt Lake | | 1-0 | | New York Red Bulls | |
| | Sep 04, 2010 | Chicago Fire | | 1-1 | | LA Galaxy | |
| Sep 04, 2010 | Philadelphia Union | | 1-1 | | Kansas City Wizards | |
| | Aug 30, 2010 | Chivas USA | | 1-0 | | DC United | |
| | Aug 29, 2010 | Colorado Rapids | | 3-0 | | Houston Dynamo | |
| Aug 29, 2010 | LA Galaxy | | 0-2 | | Kansas City Wizards | |
| Aug 29, 2010 | New England Revolution | | 1-2 | | Philadelphia Union | |
| Aug 29, 2010 | New York Red Bulls | | 2-0 | | San Jose Earthquakes | |
| Aug 29, 2010 | Seattle Sounders | | 2-1 | | Chicago Fire | |
| Aug 29, 2010 | Toronto FC | | 0-0 | | Real Salt Lake | |
| | Aug 28, 2010 | Columbus Crew | | 0-0 | | FC Dallas | |
| | Aug 22, 2010 | Columbus Crew | | 3-1 | | Colorado Rapids | |
| Aug 22, 2010 | DC United | | 2-0 | | Philadelphia Union | |
| Aug 22, 2010 | FC Dallas | | 1-0 | | Chivas USA | |
| Aug 22, 2010 | Houston Dynamo | | 4-3 | | Chicago Fire | |
| Aug 22, 2010 | Kansas City Wizards | | 4-1 | | New England Revolution | |
| | Aug 21, 2010 | San Jose Earthquakes | | 1-0 | | LA Galaxy | |
| Aug 21, 2010 | Toronto FC | | 1-4 | | New York Red Bulls | |
| | Aug 19, 2010 | Chicago Fire | | 2-1 | | New England Revolution | |
| | Aug 15, 2010 | Chivas USA | | 0-0 | | Seattle Sounders | |
| Aug 15, 2010 | DC United | | 1-3 | | FC Dallas | |
| Aug 15, 2010 | New England Revolution | | 1-0 | | Houston Dynamo | |
| Aug 15, 2010 | New York Red Bulls | | 0-1 | | LA Galaxy | |
| Aug 15, 2010 | Real Salt Lake | | 2-0 | | Columbus Crew | |
| Aug 15, 2010 | San Jose Earthquakes | | 1-0 | | Kansas City Wizards | |
| | Aug 14, 2010 | Philadelphia Union | | 1-1 | | Colorado Rapids | |
| | Aug 12, 2010 | New York Red Bulls | | 1-0 | | Toronto FC | |
| Aug 12, 2010 | Philadelphia Union | | 1-1 | | Real Salt Lake | |
| | Aug 09, 2010 | Chicago Fire | | 0-0 | | New York Red Bulls | |
| Aug 09, 2010 | FC Dallas | | 3-1 | | Philadelphia Union | |
| Aug 09, 2010 | Seattle Sounders | | 2-0 | | Houston Dynamo | |
| | Aug 08, 2010 | Colorado Rapids | | 1-0 | | San Jose Earthquakes | |
| Aug 08, 2010 | Kansas City Wizards | | 1-1 | | Real Salt Lake | |
| Aug 08, 2010 | New England Revolution | | 1-0 | | DC United | |
| | Aug 07, 2010 | Toronto FC | | 2-1 | | Chivas USA | |
| | Aug 06, 2010 | Philadelphia Union | | 1-2 | | Columbus Crew | |
| | Aug 02, 2010 | LA Galaxy | | 2-3 | | Chicago Fire | |
| | Aug 01, 2010 | Chivas USA | | 3-1 | | Columbus Crew | |
| Aug 01, 2010 | Houston Dynamo | | 2-2 | | New York Red Bulls | |
| Aug 01, 2010 | Kansas City Wizards | | 1-0 | | Toronto FC | |
| Aug 01, 2010 | Real Salt Lake | | 3-0 | | DC United | |
| Aug 01, 2010 | San Jose Earthquakes | | 0-1 | | Seattle Sounders | |
| | Jul 31, 2010 | Colorado Rapids | | 1-1 | | FC Dallas | |
| Jul 31, 2010 | Philadelphia Union | | 1-1 | | New England Revolution | |
| | Jul 26, 2010 | Seattle Sounders | | 2-1 | | Colorado Rapids | |
| | Jul 25, 2010 | Columbus Crew | | 3-0 | | Houston Dynamo | |
| Jul 25, 2010 | Real Salt Lake | | 1-1 | | Chivas USA | |
| | Jul 24, 2010 | Toronto FC | | 1-1 | | FC Dallas | |
| | Jul 23, 2010 | LA Galaxy | | 2-2 | | San Jose Earthquakes | |
| | Jul 19, 2010 | DC United | | 1-2 | | LA Galaxy | |
| Jul 19, 2010 | Houston Dynamo | | 1-1 | | Chivas USA | |
| | Jul 18, 2010 | Chicago Fire | | 0-1 | | New England Revolution | |
| Jul 18, 2010 | Colorado Rapids | | 1-1 | | Kansas City Wizards | |
| Jul 18, 2010 | Columbus Crew | | 2-0 | | New York Red Bulls | |
| Jul 18, 2010 | FC Dallas | | 2-0 | | Real Salt Lake | |
| | Jul 17, 2010 | Philadelphia Union | | 2-1 | | Toronto FC | |
| | Jul 16, 2010 | DC United | | 0-1 | | Seattle Sounders | |
| | Jul 15, 2010 | Columbus Crew | | 0-1 | | Kansas City Wizards | |
| | Jul 12, 2010 | Seattle Sounders | | 1-1 | | FC Dallas | |
| | Jul 11, 2010 | Houston Dynamo | | 0-0 | | Columbus Crew | |
| Jul 11, 2010 | Kansas City Wizards | | 0-2 | | Chivas USA | |
| Jul 11, 2010 | New England Revolution | | 2-0 | | LA Galaxy | |
| Jul 11, 2010 | New York Red Bulls | | 0-0 | | DC United | |
| Jul 11, 2010 | Philadelphia Union | | 1-2 | | San Jose Earthquakes | |
| | Jul 10, 2010 | Toronto FC | | 1-0 | | Colorado Rapids | |
| | Jul 09, 2010 | Chicago Fire | | 0-1 | | Real Salt Lake | |
| | Jul 08, 2010 | Seattle Sounders | | 2-0 | | LA Galaxy | |
| | Jul 07, 2010 | Houston Dynamo | | 1-3 | | Chivas USA | |
| | Jul 05, 2010 | Colorado Rapids | | 1-1 | | New York Red Bulls | |
| Jul 05, 2010 | LA Galaxy | | 3-1 | | Seattle Sounders | |
| | Jul 04, 2010 | Chivas USA | | 1-1 | | Philadelphia Union | |
| Jul 04, 2010 | Columbus Crew | | 2-1 | | Chicago Fire | |
| Jul 04, 2010 | FC Dallas | | 1-0 | | Kansas City Wizards | |
| Jul 04, 2010 | San Jose Earthquakes | | 1-1 | | DC United | |
| | Jul 03, 2010 | Real Salt Lake | | 5-0 | | New England Revolution | |
| | Jul 02, 2010 | Toronto FC | | 1-1 | | Houston Dynamo | |
| | Jun 28, 2010 | New England Revolution | | 0-1 | | Chicago Fire | |
| | Jun 27, 2010 | Chivas USA | | 1-2 | | FC Dallas | |
| Jun 27, 2010 | Columbus Crew | | 2-0 | | DC United | |
| Jun 27, 2010 | Houston Dynamo | | 2-2 | | Colorado Rapids | |
| Jun 27, 2010 | Kansas City Wizards | | 0-3 | | New York Red Bulls | |
| Jun 27, 2010 | Philadelphia Union | | 3-1 | | Seattle Sounders | |
| Jun 27, 2010 | Toronto FC | | 0-0 | | LA Galaxy | |
| | Jun 26, 2010 | Real Salt Lake | | 0-0 | | San Jose Earthquakes | |
| | Jun 11, 2010 | Kansas City Wizards | | 2-0 | | Philadelphia Union | |
| Jun 11, 2010 | Seattle Sounders | | 2-3 | | DC United | |
| | Jun 10, 2010 | Chicago Fire | | 2-2 | | Colorado Rapids | |
| Jun 10, 2010 | Real Salt Lake | | 1-0 | | LA Galaxy | |
| | Jun 06, 2010 | Chicago Fire | | 2-1 | | Philadelphia Union | |
| Jun 06, 2010 | Colorado Rapids | | 1-0 | | Columbus Crew | |
| Jun 06, 2010 | DC United | | 0-0 | | Real Salt Lake | |
| Jun 06, 2010 | FC Dallas | | 2-0 | | San Jose Earthquakes | |
| Jun 06, 2010 | LA Galaxy | | 4-1 | | Houston Dynamo | |
| Jun 06, 2010 | New York Red Bulls | | 1-0 | | Chivas USA | |
| Jun 06, 2010 | Seattle Sounders | | 3-0 | | New England Revolution | |
|
 League table
Fixtures
Results
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